14 August 2023
Monoclonal Antibodies Facility Design and Simulation
Designing a robust and cost-efficient monoclonal antibodies (mAbs) manufacturing facility is a significant challenge in the life sciences industry due to the difficulty of forecasting product demand and production. By integrating process simulation, coupled with capital and operating cost estimation, one can benefit from an efficient method of evaluating alternatives to find an optimized design.
18 July 2023
Enhancing Fill-Finish Facility Design with Process Simulation
The design of a fill-finish facility can be greatly enhanced with process simulation. An appropriate model can identify improvements such as higher throughput and lower cost and indicate where a variability reduction project can have the most impact.
7 July 2023
Process Architecture, Lean Manufacturing, and Simulation in Life Sciences
Process architects strive to develop a cost-effective facility that will be efficiently operated. The ideal is described in Lean manufacturing terms as minimizing non-value-added activities. The approach to “Lean” can be quantified using a model and simulations, including the facility layout and expected process variability.
26 May 2023
Yes, You Can Save Energy AND Maintain ISO Requirements!
While minimizing contamination risk seems to be at odds with saving money and creating a sustainable facility in today's biopharmaceutical companies, it is possible – even preferable – to find the balance and maintain a successful business.
4 May 2023
Lessons From a Life Sciences Rookie
Understanding the ins and outs of designing a manufacturing facility can be overwhelming if you are new to the life sciences industry. The nuances these buildings can be complex and foreign, even to the most seasoned project manager from a different industry. This blog post is about the lessons I have learned along the way.